BMP4 antibody

Catalog No. ABIN7265898

Product Details anti-BMP4 Antibody

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BMP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: BMP4 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human BMP4

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Alternative Name: BMP4 (BMP4 Products)

Synonyms: BMP2B antibody, BMP2B1 antibody, MCOPS6 antibody, OFC11 antibody, ZYME antibody, Bmp-4 antibody, Bmp2b antibody, Bmp2b-1 antibody, Bmp2b1 antibody, BOMPR4A antibody, bmp-4 antibody, zbmp-4 antibody, zgc:100779 antibody, BMP-4 antibody, XBMP-4 antibody, bmp2b antibody, bmp2b1 antibody, bmp4 antibody, ofc11 antibody, xbmp4 antibody, zyme antibody, BMP4 antibody, bone morphogenetic protein 4 antibody, bone morphogenetic protein 4 L homeolog antibody, bone morphogenetic protein 4 S homeolog antibody, BMP4 antibody, Bmp4 antibody, bmp4 antibody, bmp4.L antibody, bmp4.S antibody

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016],BMP2B, BMP2B1, MCOPS6, OFC11, ZYME,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cytokines,ESC Pluripotency and Differentiation,Growth factors,Immunology & Inflammation,NF-kB Signaling Pathway,Signal Transduction,Stem Cells,TGF-b-Smad Signaling Pathway,TGF-b-Smad Signaling Pathway_Ligands,Wnt/β-Catenin Signaling Pathway,BMP4

Molecular Weight: 47kDa

Gene ID: 652

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development