BCDIN3D antibody

Catalog No. ABIN7265842

Product Details anti-BCDIN3D Antibody

Target: BCDIN3D (BCDIN3 Domain Containing (BCDIN3D))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCDIN3D antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Bcdin3d Rabbit pAb

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of Mouse Bcdin3d.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BCDIN3D

Target: BCDIN3D (BCDIN3 Domain Containing (BCDIN3D))

Alternative Name: Bcdin3d (BCDIN3D Products)

Background: O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His, acting as a capping enzyme by protecting tRNA(His from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145, however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.,AV138748, 4930556P03Rik,Bcdin3d

Molecular Weight: 32kDa

Gene ID: 75284

UniProt: Q91YP1