BCDIN3D antibody (AA 1-292)

Catalog No. ABIN7265841

Product Details anti-BCDIN3D Antibody

Target: BCDIN3D (BCDIN3 Domain Containing (BCDIN3D))

Binding Specificity: AA 1-292

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCDIN3D antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: BCDIN3D Rabbit pAb

Sequence: MAVPTELDGG SVKETAAEEE SRVLAPGAAP FGNFPHYSRF HPPEQRLRLL PPELLRQLFP ESPENGPILG LDVGCNSGDL SVALYKHFLS LPDGETCSDA SREFRLLCCD IDPVLVKRAE KECPFPDALT FITLDFMNQR TRKVLLSSFL SQFGRSVFDI GFCMSITMWI HLNHGDHGLW EFLAHLSSLC HYLLVEPQPW KCYRAAARRL RKLGLHDFDH FHSLAIRGDM PNQIVQILTQ DHGMELICCF GNTSWDRSLL LFRAKQTIET HPIPESLIEK GKEKNRLSFQ KQ

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human BCDIN3D (NP_859059.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BCDIN3D

Target: BCDIN3D (BCDIN3 Domain Containing (BCDIN3D))

Alternative Name: BCDIN3D (BCDIN3D Products)

Synonyms: 4930556P03Rik antibody, AV138748 antibody, BCDIN3 domain containing RNA methyltransferase antibody, BCDIN3 domain containing antibody, BCDIN3D antibody, Bcdin3d antibody

Background: O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His, acting as a capping enzyme by protecting tRNA(His from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145, however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.,BCDIN3D,Cell Biology & Developmental Biology,BCDIN3D

Gene ID: 144233

UniProt: Q7Z5W3