BIRC2 antibody

Catalog No. ABIN7265820

Product Details anti-BIRC2 Antibody

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BIRC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: cIAP1 Rabbit mAb

Cross-Reactivity: Human, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human cIAP1.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BIRC2

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Alternative Name: BIRC2 (BIRC2 Products)

Background: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],API1,HIAP2,Hiap-2,MIHB,RNF48,c-IAP1,cIAP1,BIRC2,Apoptosis,Apoptosis_Caspases,Apoptosis_Death receptors & ligands,Apoptosis_Inhibition of Apoptosis,Cancer,Cell Biology & Developmental Biology,Death Receptor Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,Invasion and Metastasis,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,BIRC2

Molecular Weight: 70kDa

Gene ID: 329

UniProt: Q13490

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades