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Bcl-2 antibody (AA 1-100)

BCL2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7265813
  • Target See all Bcl-2 (BCL2) Antibodies
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Binding Specificity
    • 48
    • 36
    • 27
    • 23
    • 22
    • 21
    • 16
    • 16
    • 16
    • 11
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 401
    • 160
    • 159
    • 34
    • 23
    • 22
    • 15
    • 9
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 322
    • 107
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 319
    • 117
    Polyclonal
    Conjugate
    • 193
    • 28
    • 27
    • 20
    • 20
    • 11
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Bcl-2 antibody is un-conjugated
    Application
    • 332
    • 175
    • 141
    • 106
    • 95
    • 89
    • 80
    • 60
    • 55
    • 30
    • 23
    • 22
    • 18
    • 8
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purpose
    Bcl-2 Rabbit pAb
    Sequence
    MAHAGRTGYD NREIVMKYIH YKLSQRGYEW DAGDVGAAPP GAAPAPGIFS SQPGHTPHPA ASRDPVARTS PLQTPAAPGA AAGPALSPVP PVVHLTLRQA
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bcl-2 (NP_000624.2).
    Isotype
    IgG
    Top Product
    Discover our top product BCL2 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Alternative Name
    BCL2 (BCL2 Products)
    Background
    This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.,Bcl-2,PPP1R50,BCL2,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Autophagy,Death Receptor Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Stem Cells,BCL2
    Molecular Weight
    22kDa/26kDa
    Gene ID
    596
    UniProt
    P10415
    Pathways
    MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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