Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase, it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. [provided by RefSeq, Jul 2008],APOCIII, HALP2,Cancer,Cardiovascular,Endocrine & Metabolism,Lipid Metabolism,Lipids,Lipids_Lipoproteins/Apolipoproteins,Signal Transduction,APOC3