RED1 antibody (AA 180-380)

Catalog No. ABIN7265459

Product Details anti-RED1 Antibody

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Binding Specificity: AA 180-380

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RED1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: ADARB1 Rabbit pAb

Sequence: FETPDKAEPP FYVGSNGDDS FSSSGDLSLS ASPVPASLAQ PPLPVLPPFP PPSGKNPVMI LNELRPGLKY DFLSESGESH AKSFVMSVVV DGQFFEGSGR NKKLAKARAA QSALAAIFNL HLDQTPSRQP IPSEGLQLHL PQVLADAVSR LVLGKFGDLT DNFSSPHARR KVLAGVVMTT GTDVKDAKVI SVSTGTKCIN G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ADARB1 (NP_001103.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RED1

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Alternative Name: ADARB1 (ADARB1 Products)

Background: This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.,ADARB1,ADAR2,DRABA2,DRADA2,RED1,Epigenetics & Nuclear Signaling,ADARB1

Molecular Weight: 80kDa

Gene ID: 104

UniProt: P78563