ADAM metallopeptidase domain 32 antibody, disintegrin and metalloproteinase domain-containing protein 32 antibody, a disintegrin and metallopeptidase domain 32 antibody, ADAM32 antibody, LOC100525542 antibody, Adam32 antibody
Background
This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms.,ADAM32,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,Ubiquitin,ADAM32