ANP32B antibody

Catalog No. ABIN7265377

Product Details anti-ANP32B Antibody

Target: ANP32B (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member B (ANP32B))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ANP32B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: ANP32B Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human ANP32B

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ANP32B

Target: ANP32B (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member B (ANP32B))

Alternative Name: ANP32B (ANP32B Products)

Synonyms: APRIL antibody, PHAPI2 antibody, SSP29 antibody, 2410015B15Rik antibody, PAL31 antibody, PHAPI2a antibody, Ssp29 antibody, cb908 antibody, fa99a11 antibody, wu:fa28c10 antibody, wu:fa99a11 antibody, wu:fb40e12 antibody, zgc:77745 antibody, hLAMP-1 antibody, MGC80871 antibody, ANP32B antibody, MGC69373 antibody, SLAN antibody, acidic nuclear phosphoprotein 32 family member B antibody, acidic (leucine-rich) nuclear phosphoprotein 32 family, member B antibody, acidic nuclear phosphoprotein 32 family member B L homeolog antibody, acidic leucine-rich nuclear phosphoprotein 32 family member B antibody, ANP32B antibody, Anp32b antibody, anp32b antibody, anp32b.L antibody, LOC494442 antibody

Background: Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription. Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis. Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes. Plays also an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1. Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (By similarity.,APRIL, PHAPI2, SSP29,Apoptosis,Apoptosis_Caspases,Cell Biology & Developmental Biology,Cell Cycle,ANP32B

Molecular Weight: 29kDa

Gene ID: 10541

UniProt: Q92688