YWHAE antibody

Catalog No. ABIN7265309

Product Details anti-YWHAE Antibody

Target: YWHAE (14-3-3 epsilon (YWHAE))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This YWHAE antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: 14-3-3 epsilon Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human 14-3-3 epsilon

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for YWHAE

Target: YWHAE (14-3-3 epsilon (YWHAE))

Alternative Name: YWHAE (YWHAE Products)

Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008],14-3-3E, HEL2, KCIP-1, MDCR, MDS,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cell Biology & Developmental Biology,Cell Cycle,Cell Type Marker,Cell Type Marker_Neuron marker,Cell Type Marker_Synapse marker,Epigenetics & Nuclear Signaling,G2/M DNA Damage Checkpoint,Hippo Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Neurodegenerative Diseases Markers,Neurodegenerative Diseases_Dopamine Signaling in Parkinsons Disease,Neuroscience,PI3K-Akt Signaling Pathway,RNA Binding,Signal Transduction,Stem Cells,YWHAE

Molecular Weight: 29kDa

Gene ID: 7531

UniProt: P62258

Pathways: Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase