PCDHGA1 antibody (C-Term)

Catalog No. ABIN7233054

Product Details anti-PCDHGA1 Antibody

Target: PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))

Binding Specificity: AA 808-931, C-Term

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PCDHGA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Purpose: Anti-Protocadherin γ (pan) Mouse Monoclonal Antibody

Specificity: This antibody recognizes human, mouse, and rat PCDHG-A, B, and C proteins

Cross-Reactivity: Human, Mouse, Rat

Immunogen: Fusion protein corresponding to aa 808-931 (C-terminal cytoplasmic constant domain) of mouse PCDHGA1. This sequence is present in all 22 PCDHG proteins.

Clone: S159-5

Isotype: IgG1

Application Details

Application Notes: Immunoblotting: use at 1-2 μg/mL. A band of ~100 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their application.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: This product is stable for at least one (1) year at -20°C.

Target Details for PCDHGA1

Target: PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))

Alternative Name: Pcdhga1 (PCDHGA1 Products)

Synonyms: PCDH-GAMMA-A1 antibody, protocadherin gamma subfamily A, 1 antibody, protocadherin gamma-C5 antibody, PCDHGA1 antibody, LOC478038 antibody, Pcdhga1 antibody

Background: Protocadherin γ A1,The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. The gamma gene cluster includes 22 genes divided into 3 subfamilies: subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region (which includes 6 cadherin ectodomains and a trans-membrane region). The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins are believed to play a critical role in the establishment and function of specific cell-cell connections in the brain.

UniProt: Q91XZ0