NLRP3 antibody

Catalog No. ABIN7211585

Product Details anti-NLRP3 Antibody

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NLRP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: Detects endogenous protein by IP and WB.

Characteristics: NACHT-, LRR- and PYD-containing protein 3| CIAS1| Cryopyrin| Cold autoinflammatory syndrome 1 protein| PYPAF1| PYRIN-containing APAF1-like protein 1,NLRP3/NALP3 (human) monoclonal antibody (Nalpy3-b)

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Immunogen: Recombinant human NLRP3/NALP3 (NACHT-, LRR- and PYD-containing protein 3) (pyrin domain).

Clone: Nalpy3-b

Isotype: IgG1

Application Details

Application Notes: Immunoprecipitation (1:50)Western Blot (1:1,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. In PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze/thaw cycles.

Storage: -20 °C

Storage Comment: +4°C

Target Details for NLRP3

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Alternative Name: NALP3 (NLRP3 Products)

UniProt: Q96P20

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome