TNFRSF11A antibody (AA 60-120)
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- Target See all TNFRSF11A Antibodies
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
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Binding Specificity
- AA 60-120
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNFRSF11A antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- RANK Polyclonal Antibody
- Specificity
- The antibody detects endogenous levels of RANK
- Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
- Immunogen
- Synthesized peptide derived from part region of human RANK protein at AA range: 60-120
- Isotype
- IgG
- Top Product
- Discover our top product TNFRSF11A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:500-1:200), ELISA (1:10000-1:20000).
- Comment
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Primary Antibody
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Target
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
- Alternative Name
- RANK (TNFRSF11A Products)
- Synonyms
- RANK antibody, RGD1563614 antibody, TNFRSF11A antibody, Ly109 antibody, ODFR antibody, OFE antibody, Rank antibody, TRANCE-R antibody, mRANK antibody, CD265 antibody, FEO antibody, LOH18CR1 antibody, OPTB7 antibody, OSTS antibody, PDB2 antibody, TRANCER antibody, TNF receptor superfamily member 11A antibody, TNF receptor superfamily member 11a antibody, tumor necrosis factor receptor superfamily, member 11a, NFKB activator antibody, Tnfrsf11a antibody, TNFRSF11A antibody
- Background
- Rabbit Anti-RANK Polyclonal Antibody,Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, ODFR, Receptor activator of NF-KB, CD antigen CD265,TNFRSF11A (TNF Receptor Superfamily Member 11a) is a Protein Coding gene. Diseases associated with TNFRSF11A include Osteopetrosis, Autosomal Recessive 7 and Osteolysis, Familial Expansile. Among its related pathways are Akt Signaling and CDK-mediated phosphorylation and removal of Cdc6. The protein encoded by TNFRSF11A is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.,RANK
- Molecular Weight
- observerd band 66kDa
- Gene ID
- 8792
- UniProt
- Q9Y6Q6
- Pathways
- NF-kappaB Signaling
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