PGE Synthase antibody (Internal Region)

Catalog No. ABIN7216522

Product Details anti-PGE Synthase Antibody

Target: PGE Synthase

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGE Synthase antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: PGE synthase Polyclonal Antibody

Specificity: PGE synthase Polyclonal Antibody detects endogenous levels of PGE synthase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human PGE synthase

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PGE Synthase

Target: PGE Synthase

Abstract: PGE Synthase Products

Background: Rabbit Anti-PGE synthase Polyclonal Antibody,PTGES, MGST1L1, MPGES1, PGES, PIG12, Prostaglandin E synthase, Microsomal glutathione S-transferase 1-like 1, MGST1-L1, Microsomal prostaglandin E synthase 1, MPGES-1, p53-induced gene 12 protein,Prostaglandin E synthase encoded by PTGES is a glutathione-dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.,Prostaglandin E synthase

Molecular Weight: observerd band 17kDa

Gene ID: 9536

UniProt: O14684