Myosin Heavy Chain antibody

Catalog No. ABIN7211938

Product Details anti-Myosin Heavy Chain Antibody

Target: Myosin Heavy Chain

Reactivity: Human, Mouse, Rat, Drosophila melanogaster, Nematode

Host: Mouse

Clonality: Monoclonal

Conjugate: This Myosin Heavy Chain antibody is un-conjugated

Application: Immunofluorescence (IF)

Purpose: Myosin Heavy Chain Monoclonal Antibody

Specificity: The antibody detects endogenous MHC proteins.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

Immunogen: Synthetic Peptide

Isotype: IgG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:100).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Myosin Heavy Chain

Target: Myosin Heavy Chain

Abstract: Myosin Heavy Chain Products

Synonyms: SM2 antibody, SSMHC antibody, myosin antibody, myosin-7B antibody, MYH4 antibody, myosin, heavy chain 7B, cardiac muscle, beta antibody, myosin heavy chain 1 antibody, MYH7B antibody, MYH1 antibody

Background: Mouse Anti-Myosin Heavy Chain Monoclonal Antibody,Myosin Heavy Chain,Skeletal muscle Myosin or myosin II is the motor protein that generates force to drive muscle contraction. It is a 520 kDa hexamer comprised of two heavy chains and four light chains. Myosin heavy chain is 220 kDa in size and consists of a long coiled-coil domain tail that mediates dimerization of the two heavy chains and a globular head region that mediates ATP-dependent sliding of actin filaments. Myosin heavy chain can be proteolytically cleaved to produce heavy meromyosin, which includes the S1 motor domain (head region) and first third of the coiled coil domain, and light meromyosin, which includes the C-terminal two thirds of the coiled coil domain.,Myosin Heavy Chain

Molecular Weight: observerd band 220kDa