MRGPRX2 antibody (AA 250-330)
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- Target See all MRGPRX2 Antibodies
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
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Binding Specificity
- AA 250-330
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MRGPRX2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Purpose
- MRGX2 Polyclonal Antibody
- Specificity
- The antibody detects endogenous levels of MRGX2 protein
- Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
- Immunogen
- Synthesized peptide derived from part region of human MRGX2 protein at AA range: 250-330
- Isotype
- IgG
- Top Product
- Discover our top product MRGPRX2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
- Comment
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Primary Antibody
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Target
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
- Alternative Name
- MRGX2 (MRGPRX2 Products)
- Synonyms
- MRGX2 antibody, G370024M05Rik antibody, MrgB10 antibody, Mrgprb10 antibody, MrgB1 antibody, Mrgprb1 antibody, MAS related GPR family member X2 antibody, MAS-related GPR, member X2 antibody, MRGPRX2 antibody, Mrgprx2 antibody
- Background
- Rabbit Anti-MRGX2 Polyclonal Antibody,Mas-related G-protein coupled receptor member X2,Mast cell-specific receptor for basic secretagogues, i.e. Cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed: 25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.,MRGX2
- Molecular Weight
- observerd band 36kDa
- Gene ID
- 117194
- UniProt
- Q96LB1
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