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RORB antibody (AA 385-470) (Biotin)

RORB Reactivity: Mouse, Rat WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN715873
  • Target See all RORB Antibodies
    RORB (RAR-Related Orphan Receptor B (RORB))
    Binding Specificity
    • 14
    • 9
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 385-470
    Reactivity
    • 47
    • 26
    • 25
    • 8
    • 8
    • 8
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Mouse, Rat
    Host
    • 53
    • 8
    Rabbit
    Clonality
    • 53
    • 8
    Polyclonal
    Conjugate
    • 28
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RORB antibody is conjugated to Biotin
    Application
    • 47
    • 22
    • 19
    • 13
    • 13
    • 8
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RORB
    Isotype
    IgG
    Top Product
    Discover our top product RORB Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    RORB (RAR-Related Orphan Receptor B (RORB))
    Alternative Name
    ROR beta (RORB Products)
    Synonyms
    RORB antibody, Nr1f2 antibody, LOC100226267 antibody, NR1F2 antibody, ROR-BETA antibody, RZR-BETA antibody, RZRB antibody, bA133M9.1 antibody, nr1f2 antibody, rzrb antibody, sb:eu943 antibody, RZR-beta antibody, Rorbeta antibody, RAR related orphan receptor B antibody, RAR-related orphan receptor B antibody, RAR-related orphan receptor beta antibody, RORB antibody, Rorb antibody, rorb antibody
    Background

    Synonyms: NR1F2, Nuclear receptor ROR-beta, Nuclear receptor RZR beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, RAR related orphan receptor B, RAR related orphan receptor beta, Retinoic acid binding receptor beta, Retinoid-related orphan receptor-beta, ROR BETA, Rorb, RORB_HUMAN, RZR BETA, RZRB.

    Background: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)

    Gene ID
    6096
    UniProt
    Q92753
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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