Renin antibody (AA 331-406)

Catalog No. ABIN715436

Product Details anti-Renin Antibody

Target: Renin (REN)

Binding Specificity: AA 331-406

Reactivity: Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Renin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Dog, Mouse, Rat

Predicted Reactivity: Human,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Renin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Renin antibody (ABIN715436)

Wu, Guo, Su, Wu, Li: "Biocharacterization of Heat Shock Protein 90 in Acetaminophen-Treated Livers Without Conspicuous Drug Induced Liver Injury." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 43, Issue 4, pp. 1562-1570, (2017) (PubMed).

Soto, Melo, Marchesi, Lopes, Veras, Oliveira, Souza, de Castro, Furukawa, Saldiva, Heimann: "Exposure to fine particulate matter in the air alters placental structure and the renin-angiotensin system." in: PLoS ONE, Vol. 12, Issue 8, pp. e0183314, (2017) (PubMed).

Liu, Jiang, Zhang, Li, Li, Xie, Hu: "Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system." in: BMC cardiovascular disorders, Vol. 16, Issue 1, pp. 192, (2016) (PubMed).

Wanka, Staar, Lutze, Peters, Hildebrandt, Beck, Bäumgen, Albers, Krieg, Zimmermann, Sczodrok, Schäfer, Hoffmann, Peters: "Anti-necrotic and cardioprotective effects of a cytosolic renin isoform under ischemia-related conditions." in: Journal of molecular medicine (Berlin, Germany), (2015) (PubMed).

Target Details for Renin

Target: Renin (REN)

Alternative Name: Renin (REN Products)

Synonyms: HNFJ2 antibody, RATRENAA antibody, RENAA antibody, Ren1 antibody, D19352 antibody, Ren antibody, Ren-1 antibody, Ren-A antibody, Ren1c antibody, Ren1d antibody, Rn-1 antibody, Rnr antibody, renin antibody, renin 1 structural antibody, REN antibody, Ren antibody, Ren1 antibody, ren antibody

Background:

Synonyms: HNFJ2, Renin, Angiotensinogenase, REN

Background: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.

Gene ID: 5972

UniProt: P00797

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour