IL1A antibody

Catalog No. ABIN7193974

Product Details anti-IL1A Antibody

Target: IL1A (Interleukin 1 alpha (IL1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human IL1A (AA: extra(155-354)) expressed in E. coli.

Clone: 6G4A5

Isotype: IgG1

Application Details

Application Notes: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: IL1A (IL1A Products)

Synonyms: IL-1A antibody, IL1 antibody, IL1-ALPHA antibody, IL1F1 antibody, IL-6 antibody, Il-1a antibody, IL-1 alpha antibody, IL-1alpha antibody, L1A antibody, interleukin 1 alpha antibody, interleukin 6 antibody, IL1A antibody, IL6 antibody, Il1a antibody

Background:

Description: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Aliases: IL1, IL-1A, IL1F1, IL1-ALPHA, IL-1 alpha

Molecular Weight: 30.6 kDa

Gene ID: 3552

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints