SIRPB1 antibody (AA 72-309)

Catalog No. ABIN7193918

Product Details anti-SIRPB1 Antibody

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Binding Specificity: AA 72-309

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIRPB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human CD172b (AA: extra 72-309) expressed in E. coli.

Clone: 1A1F4

Isotype: IgG2b

Application Details

Application Notes: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for SIRPB1

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Alternative Name: CD172b (SIRPB1 Products)

Synonyms: CD172b antibody, SIRP-BETA-1 antibody, SIRPB1 antibody, SIRPG antibody, signal regulatory protein beta 1 antibody, signal-regulatory protein beta-1 antibody, signal-regulatory protein beta-1 isoform 3 antibody, SIRPB1 antibody, LOC458036 antibody, LOC458430 antibody, LOC485809 antibody, LOC715912 antibody, LOC100458151 antibody

Background:

Description: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: SIRPB1, SIRP-BETA-1

Molecular Weight: 43.2 kDa

Gene ID: 10326