SIRPB1 antibody (AA 72-309)

Catalog No. ABIN7193917

Product Details anti-SIRPB1 Antibody

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Binding Specificity: AA 72-309

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIRPB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: CD172b Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD172b (AA: 72-309) expressed in E. Coli.

Clone: 1B1G4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/50 - 1/200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for SIRPB1

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Alternative Name: CD172b (SIRPB1 Products)

Background:

Description:

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: SIRPB1, SIRP-BETA-1

Molecular Weight: 43.2kDa

Gene ID: 10326

UniProt: O00241