TLR10 antibody

Catalog No. ABIN7193787

Product Details anti-TLR10 Antibody

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR10 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: TLR10 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TLR10 (AA: extra(20-219)) expressed in E. Coli.

Clone: 2A10A4

Isotype: IgG2a

Application Details

Application Notes:

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TLR10

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Alternative Name: TLR10 (TLR10 Products)

Synonyms: TLR10 antibody, CD290 antibody, toll like receptor 10 antibody, toll-like receptor 10 antibody, TLR10 antibody, Tlr10 antibody

Background:

Description:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

Aliases: CD290

Molecular Weight: 94.6kDa

Gene ID: 81793

UniProt: Q9BXR5

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades