MICB antibody (AA 23-309)

Catalog No. ABIN7193766

Product Details anti-MICB Antibody

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Binding Specificity: AA 23-309

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MICB antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: MICB Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MICB (AA: 23-309) expressed in HEK293-6e cells supernatant.

Clone: 1B2F11

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for MICB

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Alternative Name: MICB (MICB Products)

Synonyms: PERB11.2 antibody, MHC class I polypeptide-related sequence B antibody, MHC class I-related protein-like antibody, MICB antibody, LOC512825 antibody

Background:

Description:

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Aliases: PERB11.2

Molecular Weight: 42.6kDa

Gene ID: 4277

UniProt: Q29980

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response