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MSH6 antibody (AA 374-540)

MSH6 Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 2E3A10 unconjugated
Catalog No. ABIN7193700
  • Target See all MSH6 Antibodies
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Binding Specificity
    • 15
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 374-540
    Reactivity
    • 74
    • 34
    • 27
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 56
    • 15
    • 3
    Mouse
    Clonality
    • 44
    • 30
    Monoclonal
    Conjugate
    • 42
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MSH6 antibody is un-conjugated
    Application
    • 51
    • 24
    • 23
    • 17
    • 14
    • 13
    • 11
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human MSH6 (AA: 374-540) expressed in E. coli.
    Clone
    2E3A10
    Isotype
    IgG2b
    Top Product
    Discover our top product MSH6 Primary Antibody
  • Application Notes
    WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Alternative Name
    MSH6 (MSH6 Products)
    Synonyms
    GTBP antibody, GTMBP antibody, HNPCC5 antibody, HSAP antibody, p160 antibody, cb326 antibody, wu:fb36c12 antibody, LOC100227810 antibody, AU044881 antibody, AW550279 antibody, Gtmbp antibody, mutS homolog 6 antibody, mutS homolog 6 (E. coli) antibody, DNA mismatch repair protein antibody, MSH6 antibody, msh6 antibody, Msh6 antibody
    Background

    Description: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.

    Aliases: GTBP, HSAP, p160, GTMBP, HNPCC5

    Molecular Weight
    152.8 kDa
    Gene ID
    2956
    Pathways
    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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