Claudin 6 antibody

Catalog No. ABIN7193684

Product Details anti-Claudin 6 Antibody

Target: Claudin 6 (CLDN6)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Claudin 6 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CLDN6 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CLDN6 (AA: extra(29-81) and extra(138-160)) expressed in E. Coli.

Clone: 8G5D2

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Claudin 6

Target: Claudin 6 (CLDN6)

Alternative Name: CLDN6 (CLDN6 Products)

Synonyms: cldn4l2 antibody, cldn6 antibody, CLDN6 antibody, AL024037 antibody, claudin 6, gene 1 L homeolog antibody, claudin 6 antibody, cldn6.1.L antibody, CLDN6 antibody, Cldn6 antibody

Background:

Description:

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]

Aliases: CLDN6

Molecular Weight: 23.3kDa

Gene ID: 9074

UniProt: P56747

Pathways: Hepatitis C