CDKN1C antibody
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- Target See all CDKN1C Antibodies
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CDKN1C antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
- Purpose
- CDKN1C Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CDKN1C expressed in E. Coli.
- Clone
- 8G5D5
- Isotype
- IgG1
- Top Product
- Discover our top product CDKN1C Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200-1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
- Alternative Name
- CDKN1C (CDKN1C Products)
- Synonyms
- BWCR antibody, BWS antibody, KIP2 antibody, WBS antibody, p57 antibody, p57Kip2 antibody, cb961 antibody, p27Xic1-a antibody, zgc:86618 antibody, AL024410 antibody, CDKI antibody, Kip2 antibody, p57(kip2) antibody, p57KIP2 antibody, cyclin dependent kinase inhibitor 1C antibody, cyclin-dependent kinase inhibitor 1Ca antibody, cyclin-dependent kinase inhibitor 1C (P57) antibody, cyclin-dependent kinase inhibitor 1C antibody, CDKN1C antibody, cdkn1ca antibody, Cdkn1c antibody
- Background
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Description:
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Aliases: BWS, WBS, p57, BWCR, KIP2, p57Kip2
- Molecular Weight
- 32.2kDa
- Gene ID
- 1028
- UniProt
- P49918
- Pathways
- Cell Division Cycle, Dopaminergic Neurogenesis
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