TET2 antibody

Catalog No. ABIN7193624

Product Details anti-TET2 Antibody

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TET2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human TET2 expressed in E. coli.

Clone: 5H8C7

Isotype: IgG1

Application Details

Application Notes: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, ICC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for TET2

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Alternative Name: TET2 (TET2 Products)

Synonyms: KIAA1546 antibody, MDS antibody, Ayu17-449 antibody, E130014J05Rik antibody, mKIAA1546 antibody, RGD1311625 antibody, tet methylcytosine dioxygenase 2 antibody, TET2 antibody, Tet2 antibody

Background:

Description: The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.

Aliases: MDS, KIAA1546

Molecular Weight: 223.8 kDa

Gene ID: 54790

Pathways: Warburg Effect