CD137 antibody (AA 214-255)
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- Target See all CD137 (TNFRSF9) Antibodies
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
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Binding Specificity
- AA 214-255
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD137 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS), Western Blotting (WB)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CD137 (AA: 214-255) expressed in E. coli.
- Clone
- 2A12C2
- Isotype
- IgG1
- Top Product
- Discover our top product TNFRSF9 Primary Antibody
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- Application Notes
- WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
- Alternative Name
- CD137 (TNFRSF9 Products)
- Synonyms
- TNFRSF9 antibody, zgc:136557 antibody, 4-1BB antibody, CD137 antibody, CDw137 antibody, ILA antibody, A930040I11Rik antibody, AA408498 antibody, AI325004 antibody, Cd137 antibody, Ly63 antibody, tumor necrosis factor receptor superfamily member 9 antibody, TNF receptor superfamily member 9 antibody, tumor necrosis factor receptor superfamily, member 9a antibody, tumor necrosis factor receptor superfamily, member 9 antibody, TNFRSF9 antibody, tnfrsf9a antibody, Tnfrsf9 antibody
- Background
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Aliases: TNFRSF9, ILA, 4-1BB, CDw137
- Molecular Weight
- 27.9 kDa
- Gene ID
- 3604
- Pathways
- Cancer Immune Checkpoints
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