SPA17 antibody (AA 1-152)

Catalog No. ABIN7193607

Product Details anti-SPA17 Antibody

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Binding Specificity: AA 1-152

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPA17 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: SP17 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SP17 (AA: 1-152) expressed in E. Coli.

Clone: 3G9F3

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for SPA17

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Alternative Name: SP17 (SPA17 Products)

Synonyms: spa17 antibody, MGC89454 antibody, SPA17 antibody, CT22 antibody, SP17 antibody, SP17-1 antibody, Sp17 antibody, sperm autoantigenic protein 17 antibody, sperm autoantigenic protein 17 L homeolog antibody, spa17 antibody, SPA17 antibody, spa17.L antibody, Spa17 antibody

Background:

Description:

This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009]

Aliases: CT22, SPA17, SP17-1

Molecular Weight: 17.4 kDa

Gene ID: 53340

UniProt: Q15506