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MYLK antibody (AA 1375-1524)

MYLK Reactivity: Human, Mouse WB, ELISA, IHC, ICC, FACS Host: Mouse Monoclonal 7F2B11 unconjugated
Catalog No. ABIN7193606
  • Target See all MYLK Antibodies
    MYLK (Myosin Light Chain Kinase (MYLK))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1375-1524
    Reactivity
    • 78
    • 41
    • 36
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 87
    • 3
    • 3
    • 1
    Mouse
    Clonality
    • 82
    • 12
    Monoclonal
    Conjugate
    • 41
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYLK antibody is un-conjugated
    Application
    • 38
    • 35
    • 24
    • 13
    • 13
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human MYLK (AA:1375-1524) expressed in E. coli.
    Clone
    7F2B11
    Isotype
    IgG1
  • Application Notes
    WB:1:500 - 1:2000, IHC:1:200 - 1:1000, ICC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    MYLK (Myosin Light Chain Kinase (MYLK))
    Alternative Name
    MYLK (MYLK Products)
    Synonyms
    AAT7 antibody, KRP antibody, MLCK antibody, MLCK1 antibody, MLCK108 antibody, MLCK210 antibody, MSTP083 antibody, MYLK1 antibody, smMLCK antibody, 9530072E15Rik antibody, A930019C19Rik antibody, AW489456 antibody, Mlck antibody, SMMLCK antibody, mlck antibody, fj60a06 antibody, mlck1a antibody, mylk antibody, wu:fj60a06 antibody, zmlck1 antibody, myosin light chain kinase antibody, myosin, light polypeptide kinase antibody, myosin, light chain kinase a antibody, MYLK antibody, Mylk antibody, mylka antibody
    Background

    Description: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

    Aliases: KRP, AAT7, MLCK, MLCK1, MMIHS, MYLK1, s mMLCK, MLCK108, MLCK210, MSTP083

    Molecular Weight
    210 kDa
    Gene ID
    4638
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