RRM1 antibody (AA 541-792)

Catalog No. ABIN7193575

Product Details anti-RRM1 Antibody

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Binding Specificity: AA 541-792

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RRM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: RRM1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RRM1 (AA: 541-792) expressed in E. Coli.

Clone: 2D6D8

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for RRM1

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Alternative Name: RRM1 (RRM1 Products)

Background:

Description:

This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.

Aliases: R1, RR1, RIR1

Molecular Weight: 90kDa

Gene ID: 6240

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity