RRM1 antibody (AA 541-792)
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- Target See all RRM1 Antibodies
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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Binding Specificity
- AA 541-792
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RRM1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purpose
- RRM1 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human RRM1 (AA: 541-792) expressed in E. Coli.
- Clone
- 2D6D8
- Isotype
- IgG2a
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- Application Notes
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ELISA: 1/10000
FCM: 1/200-1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
- Alternative Name
- RRM1 (RRM1 Products)
- Synonyms
- CG5371 antibody, DmRNR1 antibody, Dmel\\CG5371 antibody, RNR1 antibody, RnrM1 antibody, RntL antibody, l(2)k06709 antibody, XRRM1 antibody, R1 antibody, RIR1 antibody, RR1 antibody, CHUNP6866 antibody, cb396 antibody, cb838 antibody, r1 antibody, sb:cb548 antibody, wu:fb39b07 antibody, wu:fi14b02 antibody, wu:fk95f07 antibody, ribonucleotide reductase catalytic subunit M1 antibody, Ribonucleoside diphosphate reductase large subunit antibody, ribonucleoside-diphosphate reductase large subunit antibody, ribonucleotide reductase M1 L homeolog antibody, ribonucleotide reductase M1 antibody, ribonucleotide reductase M1 polypeptide antibody, RRM1 antibody, RnrL antibody, LOC100472317 antibody, rrm1 antibody, rrm1.L antibody, Rrm1 antibody
- Background
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Description:
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.
Aliases: R1, RR1, RIR1
- Molecular Weight
- 90kDa
- Gene ID
- 6240
- UniProt
- P23921
- Pathways
- Positive Regulation of Endopeptidase Activity
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