CD163 antibody (AA 42-259)

Catalog No. ABIN7193515

Product Details anti-CD163 Antibody

Target: CD163

Binding Specificity: AA 42-259

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD163 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Purpose: CD163 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD163 (AA: 42-259) expressed in E. Coli.

Clone: 8B7D11

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CD163

Target: CD163

Alternative Name: CD163 (CD163 Products)

Background:

Description:

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Aliases: M130, MM130, SCARI1

Molecular Weight: 125.4kDa

Gene ID: 9332

UniProt: Q86VB7