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MSH2 antibody (AA 442-586)

Name: MSH2 antibody (AA 442-586)
Brand: antibodies-online
SKU: ABIN7193508
Price: 511.5 USD
Availability: InStock

MSH2 Reactivity: Human WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 2E2C7 unconjugated

Western blot analysis using MSH2 mAb against human MSH2 (AA: 442-586) recombinant protein. (MSH2 antibody (AA 442-586))

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using MSH2 mouse mAb with DAB staining. (MSH2 antibody (AA 442-586))

IHC

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng) (MSH2 antibody (AA 442-586))

ELISA

Western blot analysis using MSH2 mAb against HEK293 (1) and MSH2 (AA: 442-586)-hIgGFc transfected HEK293 (2) cell lysate. (MSH2 antibody (AA 442-586))

Western blot analysis using MSH2 mouse mAb against Hela (1), NIH/3T3 (2), A549 (3), and A431 (4) cell lysate. (MSH2 antibody (AA 442-586))

Flow cytometric analysis of Hela cells using MSH2 mouse mAb (green) and negative control (red). (MSH2 antibody (AA 442-586))

FACS

Immunofluorescence analysis of Hela cells using MSH2 mouse mAb. (MSH2 antibody (AA 442-586))

Immunofluorescence analysis of Hela cells using MSH2 mouse mAb (green). (MSH2 antibody (AA 442-586))

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using MSH2 mouse mAb with DAB staining. (MSH2 antibody (AA 442-586))

IHC

9 images

Catalog No. ABIN7193508

Datasheet as PDF

Target See all MSH2 Antibodies

MSH2 (Mismatch Repair Protein 2 (MSH2))
Binding Specificity
15

8

8

7

7

6

6

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 442-586
Reactivity
79

39

20

6

6

4

4

3

3

3

3

2

2

1

1

1
Human
Host
76

17

1
Mouse
Compatible Secondaries
Clonality
72

23
Monoclonal
Conjugate
60

5

5

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MSH2 antibody is un-conjugated
Application
55

36

28

21

21

14

13

11

11

9

7

4

3

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose

MSH2 Antibody

Purification

Purified antibody

Immunogen

Purified recombinant fragment of human MSH2 (AA: 442-586) expressed in E. Coli.

Clone

2E2C7

Isotype

IgG1
anti-Mismatch Repair Protein 2 (MSH2) (AA 327-427) antibody
MSH2 Reactivity: Human WB, IHC, FACS, StM Host: Mouse Monoclonal MSH2-2622 unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 1-300) antibody
MSH2 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 1-934) antibody
MSH2 Reactivity: Human WB, IF, PLA Host: Rabbit Polyclonal unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 337-583) antibody
MSH2 Reactivity: Human, Mouse, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 442-586) antibody
MSH2 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 4F10D6 unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 835-934) antibody
MSH2 Reactivity: Human WB, ELISA, PLA Host: Mouse Monoclonal 4B2 unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 224-313) antibody
MSH2 Reactivity: Human IHC, StM Host: Mouse Monoclonal SYP-3551 unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 637-665) antibody
MSH2 Reactivity: Human WB, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 2-254) antibody
MSH2 Reactivity: Human WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (C-Term) antibody
MSH2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target

MSH2 (Mismatch Repair Protein 2 (MSH2))

Alternative Name

MSH2 (MSH2 Products)

Synonyms

COCA1 antibody, FCC1 antibody, HNPCC antibody, HNPCC1 antibody, LCFS2 antibody, AI788990 antibody, wu:fc06b02 antibody, wu:fc13e09 antibody, zgc:55333 antibody, ATMSH2 antibody, MUTS homolog 2 antibody, msh2 antibody, mutS homolog 2 antibody, mutS homolog 2 (E. coli) antibody, MUTS homolog 2 antibody, mutS homolog 2 L homeolog antibody, MutS protein homolog 2 antibody, MSH2 antibody, Msh2 antibody, msh2 antibody, msh2.L antibody

Background

Description:
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Aliases: FCC1, COCA1, HNPCC, LCFS2, hMSH2, HNPCC1

Molecular Weight

104.7kDa

Gene ID

4436

UniProt

P43246

Pathways

DNA Damage Repair, Production of Molecular Mediator of Immune Response