CYLD antibody (AA 204-358)

Catalog No. ABIN7193504

Product Details anti-CYLD Antibody

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Binding Specificity: AA 204-358

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYLD antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CYLD Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CYLD (AA: 204-358) expressed in E. Coli.

Clone: 5F7F4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CYLD

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Alternative Name: CYLD (CYLD Products)

Background:

Description:

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Aliases: EAC, MFT, SBS, TEM, BRSS, CDMT, MFT1, CYLD1, CYLDI, USPL2

Molecular Weight: 107.3kDa

Gene ID: 1540

UniProt: Q9NQC7

Pathways: Apoptosis, Activation of Innate immune Response