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MSH2 antibody (AA 442-586)

Name: MSH2 antibody (AA 442-586)
Brand: antibodies-online
SKU: ABIN7193496
Price: 511.5 USD
Availability: InStock

MSH2 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 4F10D6 unconjugated

Western blot analysis using MSH2 mAb against human MSH2 (AA: 442-586) recombinant protein. (MSH2 antibody (AA 442-586))

Flow cytometric analysis of Hela cells using MSH2 mouse mAb (green) and negative control (red). (MSH2 antibody (AA 442-586))

FACS

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng) (MSH2 antibody (AA 442-586))

ELISA

Western blot analysis using MSH2 mAb against HEK293 (1) and MSH2 (AA: 442-586)-hIgGFc transfected HEK293 (2) cell lysate. (MSH2 antibody (AA 442-586))

4 images

Catalog No. ABIN7193496

Datasheet as PDF

Target See all MSH2 Antibodies

MSH2 (Mismatch Repair Protein 2 (MSH2))
Binding Specificity
15

8

8

7

7

6

6

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 442-586
Reactivity
79

41

20

6

6

6

4

3

3

3

3

2

2

1

1

1
Human
Host
76

17

1
Mouse
Compatible Secondaries
Clonality
72

23
Monoclonal
Conjugate
60

5

5

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MSH2 antibody is un-conjugated
Application
57

36

28

22

21

14

13

12

11

9

7

4

3

2

1

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification

purified

Immunogen

Purified recombinant fragment of human MSH2 (AA: 442-586) expressed in E. coli.

Clone

4F10D6

Isotype

IgG2b

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MSH2 Reactivity: Human IHC, StM Host: Mouse Monoclonal SYP-3551 unconjugated

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anti-Mismatch Repair Protein 2 (MSH2) (C-Term) antibody
MSH2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions

For Research Use only
Buffer

Purified antibody in PBS with 0.05 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

4°C, -20°C for long term storage
Target

MSH2 (Mismatch Repair Protein 2 (MSH2))

Alternative Name

MSH2 (MSH2 Products)

Synonyms

COCA1 antibody, FCC1 antibody, HNPCC antibody, HNPCC1 antibody, LCFS2 antibody, AI788990 antibody, wu:fc06b02 antibody, wu:fc13e09 antibody, zgc:55333 antibody, ATMSH2 antibody, MUTS homolog 2 antibody, msh2 antibody, mutS homolog 2 antibody, mutS homolog 2 (E. coli) antibody, MUTS homolog 2 antibody, mutS homolog 2 L homeolog antibody, MutS protein homolog 2 antibody, MSH2 antibody, Msh2 antibody, msh2 antibody, msh2.L antibody

Background

Description: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Aliases: FCC1, COCA1, HNPCC, LCFS2, hMSH2, HNPCC1

Molecular Weight

104.7 kDa

Gene ID

4436

Pathways

DNA Damage Repair, Production of Molecular Mediator of Immune Response