FGFR4 antibody (AA 22-369)

Catalog No. ABIN7193466

Product Details anti-FGFR4 Antibody

Target: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Binding Specificity: AA 22-369

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGFR4 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CD334 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD334 (AA: 22-369) expressed in E. Coli.

Clone: 3B5B8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for FGFR4

Target: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Alternative Name: CD334 (FGFR4 Products)

Synonyms: FGFR4 antibody, XFGFR-4 antibody, XFGFR-4a antibody, cd334 antibody, fgfr-4 antibody, jtk2 antibody, tkf antibody, xfgfr4 antibody, CD334 antibody, JTK2 antibody, TKF antibody, Fgfr-4 antibody, etID309818.21 antibody, wu:fc13h10 antibody, zgc:111935 antibody, fgfr-4c antibody, fgfr4 antibody, fibroblast growth factor receptor 4 antibody, fibroblast growth factor receptor 4 S homeolog antibody, FGFR4 antibody, fgfr4 antibody, Fgfr4 antibody, fgfr4.S antibody

Background:

Description:

The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]

Aliases: FGFR4, TKF, JTK2

Molecular Weight: 88kDa

Gene ID: 2264

UniProt: P22455

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding