ULBP1 antibody (AA 26-216)

Catalog No. ABIN7193457

Product Details anti-ULBP1 Antibody

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Binding Specificity: AA 26-216

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ULBP1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: ULBP1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ULBP1 (AA: 26-216) expressed in E. Coli.

Clone: 3A6F11

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for ULBP1

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Alternative Name: ULBP1 (ULBP1 Products)

Synonyms: RAET1I antibody, A430108B07Rik antibody, MULT1 antibody, ULBP1 antibody, UL16 binding protein 1 antibody, UL16 binding protein 21 antibody, NKG2D ligand 1 antibody, ULBP1 antibody, ULBP21 antibody, Ulbp1 antibody, LOC100683099 antibody

Background:

Description:

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Aliases: N2DL-1, RAET1I, NKG2DL1

Molecular Weight: 28kDa

Gene ID: 80329

UniProt: Q9BZM6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process