Lysine (K)-Specific Methyltransferase 2B (KMT2B) (AA 445-599) antibody

Catalog No. ABIN7193438

Product Details

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Binding Specificity: AA 445-599

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human KMT2D (AA: 445-599) expressed in E. coli.

Clone: 1D10F6

Isotype: IgG2b

Application Details

Application Notes: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Alternative Name: KMT2D (KMT2B Products)

Synonyms: HRX2 antibody, MLL1B antibody, MLL2 antibody, MLL4 antibody, TRX2 antibody, WBP7 antibody, lysine methyltransferase 2B antibody, KMT2B antibody

Background:

Description: The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

Aliases: ALR, KMS, MLL2, MLL4, AAD10, KABUK1, TNRC21, CAGL114

Molecular Weight: 593 kDa

Gene ID: 8085

Pathways: Warburg Effect