Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ATR antibody (AA 366-550)

ATR Reactivity: Human ELISA, WB, FACS Host: Mouse Monoclonal 3G6D2 unconjugated
Catalog No. ABIN7193431
  • Target See all ATR Antibodies
    ATR (ATR serine/threonine kinase (ATR))
    Binding Specificity
    • 11
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 366-550
    Reactivity
    • 45
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 40
    • 4
    • 2
    Mouse
    Clonality
    • 43
    • 3
    Monoclonal
    Conjugate
    • 30
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATR antibody is un-conjugated
    Application
    • 26
    • 21
    • 20
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. coli.
    Clone
    3G6D2
    Isotype
    IgG1
  • Application Notes
    WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    ATR (ATR serine/threonine kinase (ATR))
    Alternative Name
    ATR (ATR Products)
    Synonyms
    FCTCS antibody, FRP1 antibody, MEC1 antibody, SCKL antibody, SCKL1 antibody, ATR serine/threonine kinase antibody, ataxia telangiectasia and Rad3 related antibody, ATR antibody, Atr antibody
    Background

    Description: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

    Aliases: FRP1, MEC1, SCKL, FCTCS, SCKL1

    Molecular Weight
    301 kDa
    Gene ID
    545
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
You are here:
Support