TRADD antibody (AA 1-177)

Catalog No. ABIN7193412

Product Details anti-TRADD Antibody

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Binding Specificity: AA 1-177

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRADD antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: TRADD Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TRADD (AA: 1-177) expressed in E. Coli.

Clone: 3A1E8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TRADD

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Alternative Name: TRADD (TRADD Products)

Synonyms: TRADD antibody, Hs.89862 antibody, 9130005N23Rik antibody, AA930854 antibody, wu:fc59e02 antibody, zgc:103556 antibody, tradd antibody, TNFRSF1A associated via death domain antibody, conjugal transfer protein D antibody, TNFRSF1A-associated via death domain antibody, TNFRSF1A-associated via death domain L homeolog antibody, tnfrsf1a-associated via death domain antibody, TRADD antibody, traDd antibody, Tradd antibody, tradd.L antibody, tradd antibody

Background:

Description:

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]

Aliases: Hs.89862

Molecular Weight: 34.2kDa

Gene ID: 8717

UniProt: Q15628

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C