MAP3K14 antibody (AA 769-947)
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- Target See all MAP3K14 Antibodies
- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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Binding Specificity
- AA 769-947
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MAP3K14 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purpose
- MAP3K14 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human MAP3K14 (AA: 769-947) expressed in E. Coli.
- Clone
- 2G2B4
- Isotype
- IgG1
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
- Alternative Name
- MAP3K14 (MAP3K14 Products)
- Synonyms
- FTDCR1B antibody, HS antibody, HSNIK antibody, NIK antibody, F23F1.4 antibody, F23F1_4 antibody, mitogen-activated protein kinase kinase kinase 14 antibody, Nik antibody, aly antibody, mitogen-activated protein kinase kinase kinase 14 antibody, MAP3K14 antibody, Map3k14 antibody, MAPKKK14 antibody
- Background
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Description:
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
Aliases: HS, NIK, HSNIK, FTDCR1B
- Molecular Weight
- 104kDa
- Gene ID
- 9020
- UniProt
- Q99558
- Pathways
- NF-kappaB Signaling, TCR Signaling
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