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XIAP antibody (AA 1-268)

XIAP Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 4C12G10 unconjugated
Catalog No. ABIN7193408
  • Target See all XIAP Antibodies
    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
    Binding Specificity
    • 16
    • 12
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-268
    Reactivity
    • 72
    • 42
    • 29
    • 2
    • 2
    Human
    Host
    • 63
    • 10
    • 1
    Mouse
    Clonality
    • 64
    • 8
    Monoclonal
    Conjugate
    • 48
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XIAP antibody is un-conjugated
    Application
    • 67
    • 33
    • 24
    • 18
    • 14
    • 13
    • 13
    • 11
    • 7
    • 3
    • 3
    • 2
    • 2
    ELISA, Flow Cytometry (FACS)
    Purpose
    XIAP Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human XIAP (AA: 1-268) expressed in E. Coli.
    Clone
    4C12G10
    Isotype
    IgG2b
    Top Product
    Discover our top product XIAP Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
    Alternative Name
    XIAP (XIAP Products)
    Background

    Description:

    This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]

    Aliases: API3, ILP1, MIHA, XLP2, BIRC4, IAP-3, hIAP3, hIAP-3

    Molecular Weight
    56.7kDa
    Gene ID
    331
    UniProt
    P98170
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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