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SETD7 antibody (AA 107-366)

SETD7 Reactivity: Human, Rat, Monkey WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 1B3B8 unconjugated
Catalog No. ABIN7193392
  • Target See all SETD7 Antibodies
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    Binding Specificity
    • 16
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-366
    Reactivity
    • 69
    • 19
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Human, Rat, Monkey
    Host
    • 60
    • 8
    • 1
    Mouse
    Clonality
    • 58
    • 10
    • 1
    Monoclonal
    Conjugate
    • 30
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SETD7 antibody is un-conjugated
    Application
    • 54
    • 27
    • 23
    • 16
    • 13
    • 13
    • 11
    • 11
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human SETD7 (AA: 107-366) expressed in E. coli.
    Clone
    1B3B8
    Isotype
    IgG2a
    Top Product
    Discover our top product SETD7 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    Alternative Name
    SETD7 (SETD7 Products)
    Synonyms
    KMT7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, set7 antibody, zgc:101860 antibody, zgc:92330 antibody, 1600028F23Rik antibody, H3K4MT antibody, Set7 antibody, Set7/9 antibody, mKIAA1717 antibody, SET domain containing lysine methyltransferase 7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SETD7 antibody, setd7 antibody, Setd7 antibody
    Background

    Description: Histone methyltransferase that specifically monomethylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates Lys-189 of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates Lys-372 of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

    Aliases: KMT7, SET7, SET9, SET7/9

    Molecular Weight
    40.7 kDa
    Gene ID
    80854
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