KAT6B antibody (AA 1186-1318)

Catalog No. ABIN7193390

Product Details anti-KAT6B Antibody

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Binding Specificity: AA 1186-1318

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KAT6B antibody is un-conjugated

Application: ELISA

Purpose: KAT6B Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human KAT6B (AA: 1186-1318) expressed in E. Coli.

Clone: 8C8D12

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for KAT6B

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Alternative Name: KAT6B (KAT6B Products)

Synonyms: id:ibd5103 antibody, si:dkey-24f15.3 antibody, GTPTS antibody, MORF antibody, MOZ2 antibody, MYST4 antibody, ZC2HC6B antibody, qkf antibody, querkopf antibody, AI507552 antibody, B130044K16Rik antibody, MYST-4 antibody, Morf antibody, Myst4 antibody, mKIAA0383 antibody, K(lysine) acetyltransferase 6B antibody, lysine acetyltransferase 6B antibody, kat6b antibody, KAT6B antibody, Kat6b antibody

Background:

Description:

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

Aliases: qkf, MORF, MOZ2, GTPTS, MYST4, ZC2HC6B, querkopf

Molecular Weight: 231.4kDa

Gene ID: 23522

UniProt: Q8WYB5