HTRA2 antibody (AA 278-458)

Catalog No. ABIN7193389

Product Details anti-HTRA2 Antibody

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Binding Specificity: AA 278-458

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HTRA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: HTRA2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human HTRA2 (AA: 278-458) expressed in E. Coli.

Clone: 6H7A8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for HTRA2

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Alternative Name: HTRA2 (HTRA2 Products)

Background:

Description:

This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Aliases: OMI, MGCA8, PARK13, PRSS25

Molecular Weight: 48.8kDa

Gene ID: 27429

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity