HTRA2 antibody (AA 278-458)
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- Target See all HTRA2 Antibodies
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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Binding Specificity
- AA 278-458
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HTRA2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human HTRA2 (AA: 278-458) expressed in E. coli.
- Clone
- 6H7A8
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- Alternative Name
- HTRA2 (HTRA2 Products)
- Synonyms
- CG8464 antibody, DmHtrA2 antibody, Dmel\\CG8464 antibody, HtrA2/Omi antibody, Omi antibody, dOmi antibody, domi antibody, htrA2 antibody, omi antibody, HTRA2 antibody, PRSS25 antibody, OMI antibody, PARK13 antibody, AI481710 antibody, Prss25 antibody, mnd2 antibody, HTRA2-related serine protease antibody, HtrA serine peptidase 2 antibody, HtrA2 antibody, HTRA2 antibody, htra2 antibody, Htra2 antibody
- Background
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Description: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Aliases: OMI, MGCA8, PARK13, PRSS25
- Molecular Weight
- 48.8 kDa
- Gene ID
- 27429
- Pathways
- Positive Regulation of Endopeptidase Activity
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