CHD4 antibody (AA 1-194)

Catalog No. ABIN7193388

Product Details anti-CHD4 Antibody

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Binding Specificity: AA 1-194

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHD4 antibody is un-conjugated

Application: ELISA

Purpose: CHD4 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CHD4 (AA: 1-194) expressed in E. Coli.

Clone: 3D3E9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CHD4

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Alternative Name: CHD4 (CHD4 Products)

Background:

Description:

The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Aliases: CHD-4, Mi-2b, SIHIWES, Mi2-BETA

Molecular Weight: 218kDa

Gene ID: 1108

UniProt: Q14839