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VEGFR2/CD309 antibody (AA 1225-1356)

Name: VEGFR2/CD309 antibody (AA 1225-1356)
Brand: antibodies-online
SKU: ABIN7193374
Price: 511.5 USD
Availability: InStock

VEGFR2 Reactivity: Human WB, IHC, ELISA, FACS, ICC, Neut Host: Mouse Monoclonal 1A9A3 unconjugated

Western blot analysis using KDR mAb against human KDR (AA: 1225-1356) recombinant protein. (VEGFR2/CD309 antibody (AA 1225-1356))

Flow cytometric analysis of Hela cells using KDR mouse mAb (green) and negative control (red). (VEGFR2/CD309 antibody (AA 1225-1356))

FACS

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng) (VEGFR2/CD309 antibody (AA 1225-1356))

ELISA

Western blot analysis using KDR mAb against HEK293 (1) and KDR (AA: 1225-1356)-hIgGFc transfected HEK293 (2) cell lysate. (VEGFR2/CD309 antibody (AA 1225-1356))

4 images

Catalog No. ABIN7193374

Datasheet as PDF

Target See all VEGFR2/CD309 (VEGFR2) Antibodies

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
Binding Specificity
42

36

27

25

20

16

16

15

15

10

10

8

8

6

6

6

5

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1225-1356
Reactivity
312

199

145

17

9

5

3

3

3

3

1

1

1

1

1

1

1

1

1

1
Human
Host
305

50

15

1

1

1
Mouse
Compatible Secondaries
Clonality
298

75
Monoclonal
Conjugate
162

34

20

13

13

12

7

7

7

7

7

7

6

6

6

6

6

6

6

6

6

6

6

2

2

1

1

1

1

1

1

1
This VEGFR2/CD309 antibody is un-conjugated
Application
223

134

96

84

64

27

26

22

18

14

13

12

9

8

7

4

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Purification

purified

Immunogen

Purified recombinant fragment of human KDR (AA: 1225-1356) expressed in E. coli.

Clone

1A9A3

Isotype

IgG1

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VEGFR2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

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VEGFR2 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Restrictions

For Research Use only
Buffer

Purified antibody in PBS with 0.05 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

4°C, -20°C for long term storage
Target

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name

KDR (VEGFR2 Products)

Synonyms

CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody, 6130401C07 antibody, Flk-1 antibody, Flk1 antibody, Krd-1 antibody, Ly73 antibody, VEGFR-2 antibody, sVEGFR-2 antibody, Vegfr-2 antibody, FLK-1 antibody, flk-1 antibody, vegfr-2 antibody, KDR antibody, FLK/KDR antibody, flk1 antibody, flk1b antibody, kdrb antibody, si:busm1-205d10.1 antibody, si:ch211-254j6.1 antibody, si:ch211-278f21.4 antibody, wu:fc31a09 antibody, fk52c05 antibody, flk antibody, kdr antibody, kdra antibody, vegfr2 antibody, vegfr4 antibody, vegr2 antibody, wu:fk52c05 antibody, kinase insert domain receptor antibody, kinase insert domain protein receptor antibody, vascular endothelial growth factor receptor kdr-like antibody, kinase insert domain receptor (a type III receptor tyrosine kinase) antibody, kinase insert domain receptor like antibody, KDR antibody, Kdr antibody, LOC100136647 antibody, kdr antibody, kdrl antibody

Background

Description: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
Aliases: FLK1, CD309, VEGFR, VEGFR2

Molecular Weight

151.5 kDa

Gene ID

3791

Pathways

RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling