IGF2R antibody (AA 160-311)
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- Target See all IGF2R Antibodies
- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
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Binding Specificity
- AA 160-311
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IGF2R antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- CD222 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD222 (AA: 160-311) expressed in E. Coli.
- Clone
- 4F1G1
- Isotype
- IgG1
- Top Product
- Discover our top product IGF2R Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
- Alternative Name
- CD222 (IGF2R Products)
- Synonyms
- CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody
- Background
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Description:
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]
Aliases: IGF2R, MPR1, MPRI, CIMPR, M6P-R, MPR300, CI-M6PR, MPR 300, M6P/IGF2R
- Molecular Weight
- 274kDa
- Gene ID
- 3482
- UniProt
- P11717
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