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IGF2R antibody (AA 160-311)

IGF2R Reactivity: Human WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 4F1G1 unconjugated
Catalog No. ABIN7193356
  • Target See all IGF2R Antibodies
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Binding Specificity
    • 16
    • 13
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-311
    Reactivity
    • 88
    • 36
    • 19
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 68
    • 22
    Mouse
    Clonality
    • 67
    • 23
    Monoclonal
    Conjugate
    • 46
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGF2R antibody is un-conjugated
    Application
    • 34
    • 32
    • 27
    • 22
    • 14
    • 13
    • 13
    • 11
    • 7
    • 6
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human CD222 (AA: 160-311) expressed in E. coli.
    Clone
    4F1G1
    Isotype
    IgG1
    Top Product
    Discover our top product IGF2R Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Alternative Name
    CD222 (IGF2R Products)
    Synonyms
    CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody
    Background

    Description: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]

    Aliases: IGF2R, MPR1, MPRI, CIMPR, M6P-R, MPR300, CI-M6PR, MPR 300, M6P/IGF2R

    Molecular Weight
    274 kDa
    Gene ID
    3482
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