TLR9 antibody (AA 26-193)
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- Target See all TLR9 Antibodies
- TLR9 (Toll-Like Receptor 9 (TLR9))
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Binding Specificity
- AA 26-193
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TLR9 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- CD289 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD289 (AA: 26-193) expressed in E. Coli.
- Clone
- 5B10E8
- Isotype
- IgG1
- Top Product
- Discover our top product TLR9 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- TLR9 (Toll-Like Receptor 9 (TLR9))
- Alternative Name
- CD289 (TLR9 Products)
- Synonyms
- CD289 antibody, toll like receptor 9 antibody, toll-like receptor 9 antibody, TLR9 antibody, Tlr9 antibody
- Background
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Description:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Aliases: TLR9
- Molecular Weight
- 116kDa
- Gene ID
- 54106
- UniProt
- Q9NR96
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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