VPREB1 antibody (AA 20-145)

Catalog No. ABIN7193342

Product Details anti-VPREB1 Antibody

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Binding Specificity: AA 20-145

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VPREB1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CD179A Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD179A (AA: 20-145) expressed in E. Coli.

Clone: 5F8F3

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for VPREB1

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Alternative Name: CD179A (VPREB1 Products)

Synonyms: IGI antibody, IGVPB antibody, VPREB antibody, VpreB antibody, CD179a antibody, Vpreb-1 antibody, V-set pre-B cell surrogate light chain 1 antibody, immunoglobulin iota chain antibody, immunoglobulin iota chain-like antibody, pre-B lymphocyte 1 antibody, pre-B lymphocyte gene 1 antibody, VPREB1 antibody, LOC698810 antibody, LOC486411 antibody, Vpreb1 antibody

Background:

Description:

The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants.

Aliases: VPREB1, IGI, IGVPB, VPREB

Molecular Weight: 16.6kDa

Gene ID: 7441

UniProt: P12018

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size